GME in Dogs Support via Diet and Other DIY Health Interventions

In this article:
1.0 What is Granulomatous meningoencephalomyelitis (GME);

2.0 Symptoms;

3.0 Dietary Support;

4.0 Additional Health Supporting Interventions.

1.0 What is Granulomatous
      meningoencephalomyelitis (GME)

Granulomatous meningoencephalomyelitis (GME) is an acute inflammatory disease that affects the central nervous system (CNS) and causes the formation of granuloma(s). Granuloma’s are a ball-like mass of immune cells formed by the immune system in an attempt to block the passage of foreign substances. The resulting wall may occur in a single location or involve multiple locations such as the brain, spinal cord and surrounding membranes. GME can cause severe and sometimes irreversible damage to the CNS. There are multiple forms of GME...

1.1 Forms of GME

1.1.1 Focal GME

• A chronic progressive condition which typically takes 3 to 6 months to fully develop;
• Focal GME mimics the effects of space-occupying tumors/masses;
• Affects either the brain, or;
• The spinal cord.

1.1.2 Multifocal GME (also called Disseminated GME)

• An acute progressive condition, which typically takes 2 to 6 weeks to fully develop;
• Affects the brain, or;
• Brain and spinal cord;
• Most common locations affected are the;
• Lower brain stem;
• Cervical spinal cord;
• Meninges;
• This form kills 25% of its victims within the first week. 

1.1.3 Occular GME

• This form can be acute, progressive or static;
• Affects the eye region of the body;
• Either affecting the eyes unilaterally (one eye is affected) or bilaterally (two eyes are affected).

In all three forms of the disease neurological issues and pain from damage to the meningeal (protective spine and brain membranes) often result.

2.0 Symptoms

2.1 Symptoms vary by type of GME…

• Behavioural Changes;
• Blindness;
• Circling;
• Constant pressing of the body with force (hard) against objects;
• Drowsiness;
• Seizures;
• Weakness of;
• Hind legs – parapresis;
• Front and hind legs (all four limbs) – tetraparesis;

Conventional Clinical Treatment 

• As commonly prescribed by allopathic veterinarians... 
• Corticosteriodsare the most common drug used;
• When used for a prolonged period of time corticosteroids can cause major debilitation and death - for an insight into the uses, side effects and dangers of this class of drugs read here.
• Leflunomide a de novo pyrimidine synthesis inhibitor may be used;
• Raditation therapy may also be used.

Alternative NaturalTreatments to Corticosteroids 

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